The Atlas of Knowledge (http://mitpress.mit.edu/books/atlas-science) introduces a visualization framework that empowers readers to systematically extract insights from data. It teaches “timeless” knowledge to inspire designers, and provides extensive references on preferred tools and workflows for answering specific questions. The visualization framework uses a systems science approach to guide analysts; it clarifies insight needs, data scales, visualizations, graphic symbols, and graphic variables; and it deeply integrates statistical, geospatial, topical, and network visualization. The Atlas features enlightening new maps that reveal the structure and dynamics of science, technology, and innovation. Among these are forty maps from the popular Places & Spaces: Mapping Science exhibits (http://scimaps.org) that range from “Science and Society in Equilibrium” to “The Millennium Development Goals Map” to the “History of Science Fiction.” The Atlas discusses science and technology trends including data monitoring, visual analytics, and real-time visualizations.